Median survival in patients with polycythemia vera (PV), which is 1.5-3 years in the absence of therapy, has been extended to approximately 14 years overall, and to 24 years for patients younger than 60 years of age, because of new therapeutic tools.
Without treatment, around half of all people with symptomatic polycythaemia vera will die in less than two years. There is no cure, but treatment can extend the person’s life span by thinning the blood and reducing the risk of blood clots and other complications.
It usually happens during the later stages of the disease. Polycythemia vera treatments help reduce your risk of symptoms and complications. But for some people, the disease still gets worse and turns into another blood cancer, despite treatment.
Polycythemia vera (PV) is a blood cancer that begins in the marrow of your bones, the soft center where new blood cells grow. It causes your marrow to make too many red blood cells so your blood is too thick. You may be more likely to have clots, a stroke, or a heart attack.
You want to feel better, not worse. Remember that secondary polycythemia is caused by an underlying condition, most of which are well known and have multiple treatment options available. Once the underlying cause is corrected, symptoms of secondary polycythemia usually go away.
Polycythemia vera diet Eat well-balanced meals complete with fresh fruits and vegetables, whole grains, lean protein, and low-fat dairy. Ask your doctor how many calories you should consume each day to maintain a healthy weight. Also, watch how much salt you eat.
If you suffer from polycythemia vera, which is a serious disease that can result in death, you may be unable to work. In those situations, you may qualify for Social Security disability benefits.
Most cases of polycythemia vera are not inherited. This condition is associated with genetic changes that are somatic, which means they are acquired during a person’s lifetime and are present only in certain cells. In rare instances, polycythemia vera has been found to run in families.
Abstract. A 20-year-old woman presented with polycythemia vera and was treated with phlebotomy alone for eleven years, following which all clinical manifestations of the disease disappeared. The clinical remission with normal physical findings and normal peripheral blood counts has persisted for a further 11 years.
In a very recent publication, researchers at the Mayo Clinic reported worse survival for patients with PV (median, 15 years) than those with ET (median, 18 years, p < 0.05), but similar leukemia-free survival (p = 0.22).
Secondary polycythemia is defined as an absolute increase in red blood cell mass that is caused by enhanced stimulation of red blood cell production. In contrast, polycythemia vera is characterized by bone marrow with an inherent increased proliferative activity.
Polycythemia Vera Complications Blood clots can cause a heart attack or stroke. They also can cause your liver and spleen to enlarge. Blood clots in the liver and spleen can cause sudden, intense pain. Slowed blood flow also prevents enough oxygen-rich blood from reaching your organs.
Additional symptoms may occur in some affected individuals including blurred vision, ringing in the ears (tinnitus), and abnormal redness of the skin especially on the face. Eventually, the spleen becomes involved. The spleen is an organ located in upper left part of the abdomen that filters out worn out blood cells.
Dehydration is a common cause of relative polycythemia. Absolute polycythemia may be primary or secondary. Primary polycythemia ( polycythemia vera) is a spontaneous proliferation of RBCs in the bone marrow.
As a Polycythemia Vera patient, you can not give blood to the Red Cross. You can go to blood centers where they will accept blood from a PV patient for what is referred to as “therapeutic phlebotomy”. You will need to check with the respective blood center in your area.